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Studies from the World Health Organization
A vast resource with in-depth reports on the oral health benefits of xylitol.

Utilization of xylitol as a preventive substance in dentistry (PDF)
The purpose of this study is to describe, by means of a review of the specialized literature, how xylitol can be used as an anticariogenic agent, demonstrating its properties and possible mechanisms of action in the prevention and control of dental caries. Read more.
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Resistant Pneumococcal Infections
excerpt from full document by Stephanie Schrag, Bernard Beall and Scott Dowell
Xylitol is a sugar that has been used as a sweetening substitute for sucrose because it has a preventive effect against dental caries. Recent evidence suggests that in addition to inhibiting growth of Streptococcus mutans, the primary cause of dental caries, this sugar can inhibit the growth of S. pneumoniae, and possibly also of other bacterial colonizers of the nasopharynx such as H. influenza (99, 100). Read more.
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American Academy of Pediatric Dentistry
Policy on the Use of Xylitol in Caries Prevention
originating Council, Council on Clinical Affairs

The American Academy of Pediatric Dentistry (AAPD) recognizes the benefits of caries preventive strategies involving sugar substitutes, particularly xylitol, on the oral health of infants, children, adolescents, and persons with special health care needs. This policy is intended to assist oral health care professionals make informed decisions about the use of xylitol-based products in caries prevention. Read more.
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The British Dental Journal

Xylitol and Caries Prevention - is it a Magic Bullet?
Several recent publications have focused discussion on the value of xylitol in caries prevention. Some reviewers have concluded that xylitol has a unique active role in caries prevention, while other reviewers have been more cautious saying that the case is not yet proven. Chewing xylitol gum is certainly effective at preventing caries development compared with chewing sugared gum or not chewing any gum. Xylitol gum appears to be more effective than sorbitol gum or combinations of xylitol and sorbitol.
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informaworldExcellent articles for purchase

Use of xylitol chewing gum in daycare centers: a follow-up study in Savonlinna, Finland
The use of toothbrushes in daycare centers has been questioned because of the possibility of infections spreading through unsupervised brushing. Several field studies have demonstrated a caries-preventive effect of xylitol chewing gum - a measure that could be a practical way of taking care of oral hygiene during daycare hours without brushing.
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ingenta
Excellent articles for purchase

Xylitol candies in caries prevention: results of field study in Estonian children.
All field studies have unequivocally reported significant reductions in dental caries occurrence associated with the use of chewing gum containing xylitol. No other xylitol products besides chewing gum have so far been tested in field trials. A 5-year follow-up study with 2- or 3-year xylitol consumption periods began in Estonia in 1994 with 740 10-year-old children in 12 schools at baseline examinations. For the study, 3 clusters each including 3–5 schools were formed on the basis of baseline caries experience.
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